USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P13645 USC-OGP 2-DE database:  P13645 P13645 General information about the entry View entry in simple text format Entry name K1C10_HUMAN Primary accession number P13645 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Keratin, type I cytoskeletal 10; AltName: Full=Cytokeratin-10; Short=CK-10; AltName: Full=Keratin-10; Short=K10;. Gene name Name=KRT10 Synonyms=KPP Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1097: pI=5.93; Mw=142767 SPOT OGP-1105: pI=5.51; Mw=115893 SPOT OGP-1230: pI=5.28; Mw=34566 SPOT OGP-1283: pI=5.35; Mw=25790 Cross-references UniProtKB/Swiss-Prot P13645; K1C10_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name K1C10_HUMAN Primary accession number P13645 Secondary accession number(s) Q14664 Q8N175 Sequence was last modified on  November 24, 2009 (version 6) Annotations were last modified on  March 15, 2017 (version 183) Name and origin of the protein Description RecName: Full=Keratin, type I cytoskeletal 10; AltName: Full=Cytokeratin-10; Short=CK-10; AltName: Full=Keratin-10; Short=K10; Gene name Name=KRT10 Synonyms=KPP Encoded on Name=KRT10; Synonyms=KPP Keywords 3D-structure; Coiled coil; Complete proteome; Direct protein sequencing; Disease mutation; Ichthyosis; Intermediate filament; Keratin; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J04029; AAA60544.1; -; mRNA EMBL X14487; CAA32649.1; -; Genomic_DNA EMBL AC090283; -; NOT_ANNOTATED_CDS; mRNA EMBL BC034697; AAH34697.1; -; mRNA EMBL M19156; AAA59468.1; ALT_INIT; mRNA EMBL L20218; AAB59438.1; -; Genomic_DNA EMBL L20219; AAB59439.1; -; Genomic_DNA EMBL M77663; AAA59199.1; -; mRNA CCDS CCDS11377.1; -; . PIR A31994; A31994; . PIR S02158; KRHU0; . RefSeq NP_000412.3; NM_000421.3; . UniGene Hs.99936; -; . PDB 3ASW; X-ray; 2.60 A; B=473-487 PDB 4F1Z; X-ray; 2.30 A; Q=499-512 PDB 4ZRY; X-ray; 3.30 A; A=337-456 PDBsum 3ASW; -; . PDBsum 4F1Z; -; . PDBsum 4ZRY; -; . ProteinModelPortal P13645; -; . SMR P13645; -; . BioGrid 110056; 59; . IntAct P13645; 19; . MINT MINT-1132575; -; . STRING 9606.ENSP00000269576; -; . iPTMnet P13645; -; . PhosphoSitePlus P13645; -; . SwissPalm P13645; -; . BioMuta KRT10; -; . DMDM 269849769; -; . REPRODUCTION-2DPAGE P13645; -; . SWISS-2DPAGE P13645; -; . EPD P13645; -; . PaxDb P13645; -; . PeptideAtlas P13645; -; . PRIDE P13645; -; . TopDownProteomics P13645; -; . DNASU 3858; -; . Ensembl ENST00000269576; ENSP00000269576; ENSG00000186395; . GeneID 3858; -; . KEGG hsa:3858; -; . UCSC uc002hvi.4; human; . CTD 3858; -; . DisGeNET 3858; -; . GeneCards KRT10; -; . HGNC HGNC:6413; KRT10; . HPA CAB000132; -; . HPA HPA012014; -; . MalaCards KRT10; -; . MIM 113800; phenotype; . MIM 148080; gene; . MIM 607602; phenotype; . MIM 609165; phenotype; . neXtProt NX_P13645; -; . OpenTargets ENSG00000186395; -; . Orphanet 281139; Annular epidermolytic ichthyosis; . Orphanet 281190; Congenital reticular ichthyosiform erythroderma; . Orphanet 312; Epidermolytic ichthyosis; . PharmGKB PA30200; -; . eggNOG ENOG410IGJX; Eukaryota; . eggNOG ENOG410YDXS; LUCA; . GeneTree ENSGT00760000118808; -; . HOGENOM HOG000230975; -; . HOVERGEN HBG013015; -; . InParanoid P13645; -; . KO K07604; -; . OMA HGNSHQG; -; . OrthoDB EOG091G087I; -; . PhylomeDB P13645; -; . TreeFam TF332742; -; . Reactome R-HSA-6805567; Keratinization; . Reactome R-HSA-6809371; Formation of the cornified envelope; . ChiTaRS KRT10; human; . GeneWiki Keratin_10; -; . GenomeRNAi 3858; -; . PRO PR:P13645; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000186395; -; . CleanEx HS_KRT10; -; . ExpressionAtlas P13645; baseline and differential; . Genevisible P13645; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:0005882; C:intermediate filament; NAS:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0030280; F:structural constituent of epidermis; NAS:UniProtKB; . GO GO:0070268; P:cornification; TAS:Reactome; . GO GO:0031424; P:keratinization; TAS:Reactome; . GO GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB; . InterPro IPR001664; IF; . InterPro IPR018039; Intermediate_filament_CS; . InterPro IPR002957; Keratin_I; . InterPro IPR009053; Prefoldin; . PANTHER PTHR23239; PTHR23239; 1; . Pfam PF00038; Filament; 1; . PRINTS PR01248; TYPE1KERATIN; . SMART SM01391; Filament; 1; . SUPFAM SSF46579; SSF46579; 1; . PROSITE PS00226; IF; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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